Skip to main content

Grip it & RiPP it

February 11, 2019

Azol(in)es, are important and common motifs in natural products and therapeutics. They are especially abundant in ribosomally synthesized and post-translationally modified peptide natural products (RiPPs) like cyanobactins and thiopeptides and even define an entire subclass of RiPPs dubbed “linear azole-containing … Read more

A DEL of a Good Paper

July 13, 2018

DNA-encoded libraries (DELs) have been making a big splash in drug discovery recently. Although the original idea dates back to 1992, DELs seem now to be surpassing traditional high-throughput screening approaches in terms of cost, scale, and speed and promise … Read more